Biocatalysis
for the Pharmaceutical Industry: Discovery,
Development,
and Manufacturing
Biocatalysis for the
Pharmaceutical Industry: Discovery, Development, and Manufacturing.
By Junhua Tao, Guo-Qiang Lin,
Andreas Liese
·
Publisher: Wiley
·
Number Of Pages: 250
·
Publication Date: 2008-10-31
·
ISBN-10 / ASIN: 0470823143
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ISBN-13 / EAN: 9780470823149
Product Description:
Biocatalysis is rapidly evolving into a
key technology for the discovery and production of chemicals, especially in the
pharmaceutical industry, where high yielding chemo-, regio-, and
enantioselective reactions are critical. Taking the latest breakthroughs in
genomics and proteomics into consideration, Biocatalysis for the Pharmaceutical
Industry concisely yet comprehensively discusses the modern application of
biocatalysis to drug discovery, development, and manufacturing. Written by a
team of leading experts, the book offers deep insight into this cutting edge
field.
·
Covers
a wide range of topics in a systematic manner with an emphasis on industrial
applications
·
Provides
a thorough introduction to the latest biocatalysts, modern expression hosts,
state-of-the-art directed evolution, high throughput screening, and bioprocess
engineering
·
Addresses
frontier subjects such as emerging enzymes, metabolite profiling, combinatorial
biosynthesis, metabolic engineering, and autonomous enzymes for the synthesis
and development of chiral molecules, drug metabolites, and semi-synthetic
medicinal compounds and natural product analogs
·
Highlights
the impact of biocatalysis on green chemistry
·
Contains
numerous graphics to illustrate concepts and techniques
Biocatalysis for the Pharmaceutical
Industry is an essential resource for scientists, engineers, and R&D policy
makers in the fine chemical, pharmaceutical, and biotech industries. It is also
an invaluable tool for academic researchers and advanced students of organic
and materials synthesis, chemical biology, and medicinal chemistry.